Jurnal YARSI
Kandungan Vitamin A dan Protein Bakso Belut di Daerah Istimewa Yogyakarta

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Kandungan Vitamin A dan Protein Bakso Belut di Daerah Istimewa Yogyakarta
Vitamin A and Protein Content of eel (Monopterus albus) Meat Balls in the Special Region of Yogyakarta
JURNAL KEDOKTERAN YARSI 16 (3) : 181-186 (2008)
by
Yoni Suryani, Yuliati, Yuyun Farida
Department of Biology Education, Faculty of Mathematics and Science, Yogyakarta State University, Yogyakarta


ABSTRACT
The objectives of this study were to investigate vitamin A and protein contents in eel (Monopterus albus) meat balls. The eel meat balls were made by a special addition of tapioca 30%, 40%, 50% and 60% of the total weight of eel meat. Hedonic test was conducted in order to find the levels of panel list preferences. Friedman test was employed to find the effect of tapioca addition on colour, flavour, texture and taste. The content of vitamin A was analysed using HPLC method and protein content using Micro Kjeldahl method. The result revealed that the variation of tapioca addition gave no significant effect on colour performance with the significance level of 1.0. However, it gave significant effect on flavour, texture and taste preferences with the significance level of <0.05. It was found that the most favourite eel meat balls was the one with tapioca addition of 50% of the eel meat weight. The average of vitamin A content was 2,215.95 ?g/100 g and protein is 7.2896 mg/100 g on the most favourite eel meat balls.
 
Pengaruh Pemberian Ekstrak Biji Luffa acutangula, Roxb pada Mencit Betina Galur Swiss Webster terhadap Lama Siklus Estrus dan Jumlah Folikel Muda

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Pengaruh Pemberian Ekstrak Biji Luffa acutangula, Roxb pada Mencit Betina Galur Swiss Webster terhadap Lama Siklus Estrus dan Jumlah Folikel Muda
The Effect of Oral Administration of Luffa acutangula, Roxb Seed Extract on Female of Mice Swiss Webster Strain on the Estrous Cycle Period and the Number of Immature Follicles
JURNAL KEDOKTERAN YARSI 16 (3) : 199-206 (2008)
by
Endang Purwaningsih
Department of Biology, Faculty of Medicine, YARSI University Jakarta


ABSTRACT
The purpose of the present study was to investigate the effect of oral Luffa acutangula, Roxb seed extract respectively in the estrous cycle period and the total number of immature follicles on female mice, Swiss Webster strain. In this study, experimental animals were divided to 5 treatment groups. The first 3 mice of each group were treated with 200, 300 and 400 mg/kg body weight of seed extract orally. The remaining 2 mice served as treated control (given aquabidest only) and same control. Treatment wih seed extract of each group was given everyday for 20 and 40 days. All female mice which were treated with various doses (200, 300 and 400 mg/kg body weight) of Luffa acutangula, Roxb seed extract showed the highly significant different in the estrous cycle period and the number of immature follicles compared to control groups on day 20 and 40. The duration of estrous cycle of the treatment group was longer and the number of immature follicles were decreased; and the duration cycle was longer significant for the 40 day.
 
Distribusi Karakter dan Faktor Lingkungan pada Status Gizi Balita Desa Kalialang Kemangkon, Purbalingga

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Distribusi Karakter dan Faktor Lingkungan pada Status Gizi Balita Desa Kalialang Kemangkon, Purbalingga
Distribution of Characteristics and Environmental Factors on Nutritional Status of under five year Toddlers in Kalialang Village, Purbalingga
JURNAL KEDOKTERAN YARSI 16 (3) : 207-218 (2008)
by
Herke Sigarlaki
Department of Public Health, School of Medicine, University Christian of Indonesia, Jakarta


ABSTRACT
Long lasting economic crisis has various impacts to the community life and recently malnutrition cases have been emerged and easily found in several regions of the country. There were approximately around 1.5 million children suffering from malnutrition in 2004, and more or less 150 thousand among them were predicted to be suffering from marasmus, kwashiorkor and marasmus-kwashiorkor. This study was carried out employing a cross sectional approach. The population selected was a group of children coming to the study site selected by non-random sampling method. Univariate and bivariate analyses were performed both manually and using computer based approach. It was observed that up to 6.59% children suffering from malnutrition and residing at Kalialang village, Kemangkon, Purbalingga came from parents with primary school education background. Similar parents’ education background was also observed in 14.24% children suffering from under nutrition.
 
Efektivitas Residu Insektisida Actellic 500EC pada Berbagai Macam Permukaan Dinding Terhadap Kematian Nyamuk Anopheles aconitus, Aedes aegypti, dan Culex quinquefasciatus

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Efektivitas Residu Insektisida Actellic 500EC pada Berbagai Macam Permukaan Dinding Terhadap Kematian Nyamuk Anopheles aconitus, Aedes aegypti, dan Culex quinquefasciatus
The efficacy of Actellic 500 EC insecticide residue on various types of wall surface towards mortality of Anopheles aconitus, Aedes aegypti, and Culex quinquefasciatus mosquitoes
JURNAL KEDOKTERAN YARSI 16 (3) : 219-227 (2008)
by
Hasan Boesri, dan Lulus Susanti
Vector and Reservoir Disease Research and Development Institute (VRDRDI), Salatiga


ABSTRACT
Insecticide spray has been commonly practiced for malaria eradication program. Well chosen and accurate dose of insecticide is required to obtain the best result. In this study, a small scale trial of Actellic 500EC residual spray with dosage ranges of 1.0 ml/m2, 2.0 ml/m2,, 4.0 ml/m2 and 5.0 ml/m2 was applied on wall, shelf and bamboo surfaces. Three malaria vectors e.g. Anopheles aconitus, Aedes aegypti, and Culex quinquefasciatus mosquitoes, 3-4 days old and well fed were used for the experiment using bioassay test kit cone (WHO standard 1975). The result showed that 4.0 ml/m2 and 5.0 ml/m2 dosages of Actellic 500EC were more effective than the other dosages. The mosquito mortality was 100% in one week for An. aconitus, Ae. aegypti and Cx. quinquefasciatus.
 
Effect of resistance training on strength and endurance of muscle in chronic heart failure

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Effect of resistance training on strength and endurance of muscle in chronic heart failure
JURNAL KEDOKTERAN YARSI 17 (1) : 001-010 (2009)
by
Herlina Wungouw
Department of Physiology, Sam Ratulangi University, Faculty of Medicine, Manado


ABSTRACT
Resistance training (RT) has been used to increase muscle strength and endurance. In CHF patients, the effect of RT has not been thoroughly investigated. This study was conducted to explore the effect of RT to reverse muscular weaknesses and decreased muscular endurance that have been found in many CHF patients.
A prospective-randomized controlled study was used as the research design. The effect of RT on muscular strength and endurance was evaluated in 39 CHF patients with II-III New York Heart Association (NYHA) functional class and left ventricle ejection fraction (LVEF), 27±7 (mean ± standard deviation) in the exercise group and 28±6 in the control group. Initial two tests, knee extensor/flexor and elbow extensor/flexor for measuring strength and endurance were performed one week apart using isokinetic machine. After randomization (exercise group=EG and control group=CG), EG performed 3 months supervised RT in hydraulic machine using incremental approach based on individual response. All patients followed the end-point test.
The result showed that muscular strength and endurance in EG increased by 20±19% (p <.000) and 25±26% (p < .001), respectively while in the CG, strength and endurance nearly unchanged. The difference between groups was significant (p< .006 for strength and p < .003 for endurance). There was no adverse cardiac event occurred during the test and training sessions.
In conclusion, resistance training was safe for stable CHF patients and was able to increase muscular strength and endurance.
 
Deteksi Mutasi Gen Gyrase A Porphyromonas Gingivalis Resisten terhadap Ciprofloxacin berdasarkan teknik Polymerase Chain Reaction

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Deteksi Mutasi Gen Gyrase A Porphyromonas Gingivalis Resisten terhadap Ciprofloxacin berdasarkan teknik Polymerase Chain Reaction
Detection of Gyrase A Mutation of Porphyromonas Gingivalis gene resistant to Ciprofloxacin by using Polymerase Chain Reaction Technique
JURNAL KEDOKTERAN YARSI 17 (1) : 011-020 (2009)
by
Irene E.Rieuwpassa1, Mochammad Hatta2
1Department of Oral Biology, Faculty of Dentistry, Hasanuddin University
2Department of Microbiology, Molecular Biology and Immunology Laboratory, Facculty of Mediciene, Hasanuddin University, Makassar


ABSTRACT
One of resistance mechanisms to ciprofloxacin shown by bacterium Porphyromonas gingivalis isolated from periodontitis patients is mutations of genes through changes in DNA topoisomerase. Ciprofloxacin is an effective antimicrobial for Gram-negative bacteria effectively used for clinical infections treatment. The purpose of this research was to determine the gene mutation of P. gingivalis on periodontitis patients in relation to the resistance to ciprofloxacin by using disc diffusion and, followed by RFLP-PCR on P.gingivalis samples. Based on sensitivity tests by diffusion method, it was shown that the sensitive samples (n =13) had the highest inhibition zone diameter (mean= 25 mm), while the intermediate samples (n=1) was 19 mm. Examination using RFLP-PCR for 14 samples did not reveal any mutation of gyrase A gene.
 
Efek perawatan luka terkontaminasi dengan ekstrak bawang putih lanang dalam mempercepat penurunan eritema

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Efek perawatan luka terkontaminasi dengan ekstrak bawang putih lanang dalam mempercepat penurunan eritema
The effects of “lanang” onion extract on contaminated wound treatment by accelerating the reduction of erythema
JURNAL KEDOKTERAN YARSI 17 (1) : 021-030 (2009)
by
Yulian Wiji Utami1, Anis Murniati2 , Sumarno3
1Lecturer of Nursing Program, Faculty of Medicine Brawijyaya University Malang
2Student of Nursing Program, Faculty of Medicine Brawijyaya University Malang
3Lecturer of Medical Faculty of Brawijaya University Malang


ABSTRACT
This study was aimed to examine the effect of ”lanang” onion extract to accelerate the reduction of erythema inflammation sign in contaminated wound. A true experimental with posttest only control group design was used. The variable observed was a photograph of wound taken throughout the experiment which was then processed by program corel photopoint suite graphic 12, so it could provide average value of the decrease of erythema inflammation sign. Samples consisted of 4 groups, each group was composed of five rats. A series of extract concentration were applied, e.g. 128 mg/ml, 256 mg/ml, and 512 mg/ml for the first, second and third group respectively. In addition, 10% povidone iodine was used for the forth group.
The result showed that by the eighth day, the average decrease of mean red color intensity or the erythema values were 49.26, 45.44, 45.32 and 62. 96 in the first, second, third and forth group respectively. Statistical analysis employing one way ANOVA showed significant difference for all groups [o.ooo < ? (0.05)]. No different was observed on Post hoc result test in group 1 and 2 [0.352 >? (0.05)], however, significant difference [0,0000
 
Gambaran anemia gizi dan kaitannya dengan asupan serta pola makan pada tenaga kerja wanita di Tangerang, Banteng

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Gambaran anemia gizi dan kaitannya dengan asupan serta pola makan pada tenaga kerja wanita di Tangerang, Banteng
Nutrional anemia profile in relation to nutrients intake and food pattern of the female workers in Tangerang, Banten
JURNAL KEDOKTERAN YARSI 17 (1) : 031-039 (2009)
by
M. Arifin Suyardi1, Ance Andriani2, Benny L. Priyatna3
1Department of Nutrition, University of Indonesia School of Medicine, Jakarta
2Department of Nutrition, University of Kristen Indonesia School of Medicine, Jakarta
3Hiperkes DKI Jaya


ABSTRACT
Health and nutritional status of female workers are factors determining the quality of human resources in the future. A cross sectional study was done in shoes factory on cutting and trimming department in Tangerang district, Banten. This study was conducted to observe the nutritional enemia profile in this group employing questionaire, anthropometric measurement, physical and laboratory examination. The population was female workers. Subjects were chossen using inclusion criteria. A total of 125 persons were admitted in this study. Overall the prevalence of undernutrition was 23 (18.4%). Anemia was found in 78 (62.4%), consisted of 55 (44%) nutritional anemia and 23 (18.4%) unknown caused. Nutritional anemia were separated to iron deficiency anemia 44 (35.2%), B12 deficiency anemia 2 (1.6%), iron + B12 deficiency anemia 4 (3.2%), iron + folic acid deficiency anemia 2 (1.6%), B12 + folic acid deficiency anemia 2 (1.6%), iron + B12 + folic acid deficiency anemia 1 (0.8%). This study concluded that the nutritional anemia was related significantly (p<0.05) to inadequacy protein and iron intake was well as unpair food pattern. In the future, effort should be done to give adequate nutrients intake especially sources of protein, iron, folic acid and B12 vitamin.
 
Aktivitas antioksidan dan efek sitotoksik ekstrak Kola (Cola nitida) pada kulter sel kanker hati (HepG-2)

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Aktivitas antioksidan dan efek sitotoksik ekstrak Kola (Cola nitida) pada kulter sel kanker hati (HepG-2)
Antioxidant activities and cytotoxic effect of Cola nut extract (Cola nitida) on human liver carcinoma cell lines (HepG-2)
JURNAL KEDOKTERAN YARSI 17 (1) : 040-044 (2009)
by
Susi Endrini1, Himmi Marsiati1, Suherman J2, Fauziah O3, and Asmah R3
1Department of Biochemestry, Faculty of Medicine YARSI University, Jakarta
2Faculty of Medicine and Health, Muhammadiyah University of Jakarta
3Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, D.E., Malaysia


ABSTRACT
Liver cancer is one among cancers with increasing incidence in the world. Cola fruit (Cola nitida) is a fruit that is rich in properties and has been known since the Dutch colonial era. This fruit contains ingredients such as those contained in tea and chocolate such as methylxanthine and its derivatives. This study aims to determine the content of antioxidants and cytotoxic effects of cola fruit extracts obtained from Indonesia and Malaysia on liver cancer cell lines. Antioxidant content of fruit extracts of cola was assessed using DPPH (2,2-diphenyl-2-picrylhydrazyl hydrate) and cytotoxic effects were studied using MTT (3 - (4,5-Dimethylthiazol-2-Yl)-diphenyltetrazolium bromide -2.5) on human liver cancer cell lines (HepG-2). The results showed that cola fruit from Malaysia contained high antioxidant with the IC50 value of 37.2 µg/mL whereas IC50 of value of its Indonesia’s cola fruit was 66.0 ug / mL. The similar results have been shown in the cytotoxic test using HepG-2 liver cancer cell lines. Malaysia’s cola fruit extract has a smaller IC50 value of 6.5 µg / mL while the fruit extract of Indonesia’s cola showed IC50 value of 39.5 µg / mL. These values indicates that the fruit extract of cola is a potential anticancer activities especially on liver cancer. Further studies are required to clarify this hypothesis.
 
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