PROFIL SINGKAT DOSEN

Full Name : Ahmad Rusdan Handoyo Utomo, Ph.D
Email address : Ahmad.utomo@icloud.com
Academic Qualification :
  • Postdoctoral Fellow Department of Pathology Harvard Medical School, Boston USA (2003-2007)
  • PhD Molecular Medicine, University of Texas Health Science Center at San Antonio, TX, USA (1995-2003)
  • BSc Chemistry (Magna Cum Laude), Angelo State University, San Angelo TX USA (1991-1995)
No Phone Office : +62 (21) 4296675
No Fax : +62 (21) 4243171
Area of Expertise : Cancer Genetics, Immunology, Molecular Diagnostics
Research Grants :
  1. 2016 PPTIRISTEK DIKTI Pengembangan Produk Kit Diagnostik Multigen Secara non invasive sebagai Alat Diagnostik Penentu Obat dan Deteksi Kekambuhan Pasien Kanker Paru
Publications :
  1. Utomo AR, Nikitin Al Lee WH. Temporal, spatial, and cell type-specific control of Cre-mediated DNA recombination in transgenic mice. Nat Biotechnol. 1999 Nov; 17(11):1091-6.
  2. Utomo A, Jiang X, Furuta S, Yun J, Levin DS, Wang YC, Desai KV, Green JE, Chen PL, Lee WH.. Identification of a novel putative non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase (lt{PGPx) essential for alleviating oxidative stress generated from polyunsaturated fatty acids in breast cancer cells. J Biol Chem. 2004 Oct 15;279(42):43522-9.
  3. Utomo A, Cullere X, Glogauer M, Swat W, Mayadas TN. Vav proteins in neutrophils are required for FcgammaR-mediated signaling to Rac GTPases and nicotinamide adenine dinucleotide phosphate oxidase component p40(phox). J Immunol. 2006 Nov I ;177 (9):6388-97.
  4. Utomo A. et al. Requirement for Vav proteins in post-recruitment neutrophil cytotoxicity in IgG but not complement C3 dependent injury. J Immunol. 2008 May 1 ; 1 80(9):627 9-6287.
  5. Kristyanto H, Utomo AR. Pharmacogenetic application in personalized cancer treatment. Acta Med Indones. 2010 Apr;42(2):109-15.
  6. Li X, Utomo A, Cullere X, Choi MM, Milner DA Jr, Venkatesh D, Yun SH, Mayadas TN. The B-Glucan Receptor Dectin-l Activates the Integrin Mac-1 in Neutrophils via Vav Protein Signaling to Promote Candida albicans Clearance. Cell Host Microbe. 2011 Dec 15;10(6):603-15
  7. Abdullah M, Sudoyo AW, Utomo AR, Fauzi A, Rani AA. Molecular profile of colorectal cancer in Indonesia: is there another pathway? Gastroenterol Hepatol Bed Bench 2012 ;5(2):7 | -7 8.)
  8. Yatabe Y, Kerr KM, Utomo A, et al., EGFR mutation testing practices within the Asia Pacific region: Results of a multicenter diagnostic survey. J Thorac Oncol. 2014 Nov 7.
  9. Murdiyarso LS, Kartawinata M, Jenie I, Widjajahakim G, Hidajat H, Sembiring R, Nasar IM, Cornain S, Sastranagara F, Utomo AR. Single and multiple high-risk and low-risk Human Papillomavirus association with cervical lesions of 11,224 women in Jakarta. Cancer Causes Control. 2016 Oct 17.
  10. Levi M, Prayogi G, Sastranagara F, Sudianto E, Widjajahakim G, Gani W, Mahanadi A, Agnes J, Khairunisa BH, Utomo AR. Clinicopathological Associations of K-RAS and N-RAS Mutations in Indonesian Colorectal Cancer Cohort. J Gastrointest Cancer. 2017 Jan 3.
  11. Syahruddin E, Wulandari L,Sri Muktiati N,et.al Uncommon EGFR mutations in cytological specimens of 1,874 newly diagnosed Indonesian lung cancer patients. LCTT Volume 9:25–34. 2018 doi: 10.2147/LCTT.S154116
  12. Zaini J, Syahruddin E, Yunus M, et al. Evaluation of PCR‐HRM, RFLP, and direct sequencing as simple and cost effective methods to detect common EGFR mutations in plasma cell–free DNA of non–small cell lung cancer patients. Cancer Reports. 2019;e1159. https://doi.org/10.1002/cnr2.1159
  13. Masykura N, Habibah U, Selasih SF, et al. Feasibility of Qualitative Testing of BCR-ABL and JAK2 V617F in Suspected Myeloproliperative Neoplasm (MPN) using RT-PCR1 Reversed Dot Blot Hybridization (RT-PCR RDB2). Clinical Lymphoma Myeloma and Leukemia. January 2019. doi:10.1016/j.clml.2019.01.005.
  14. Masykura, N., Zaini, J., Syahruddin, E., Andarini, S. L., Hudoyo, A., Yasril, R., Ridwanuloh, A., Hidajat, H., Nurwidya, F., & Utomo, A. (2019). Impact of smoking on frequency and spectrum of K-RAS and EGFR mutations in treatment naive Indonesian lung cancer patients. Lung Cancer (Auckland, N.Z.), 10, 57–66. https://doi.org/10.2147/LCTT.S180692
  15. Sudoyo, A. W., Kurniawan, A. N., Kusumo, G. D., Putra, T. P., Rexana, F. A., Yunus, M., Budiyati, A. D., Kurniawan, D., Utama, A., & Utomo, A. R. (2019). Increased CD8 Tumor Infiltrating Lymphocytes in Colorectal Cancer Microenvironment Supports an Adaptive Immune Resistance Mechanism of PD-L1 Expression. Asian Pacific journal of cancer prevention : APJCP, 20(11), 3421–3427. https://doi.org/10.31557/APJCP.2019.20.11.3421
  16. Illian, D., Siregar, E.S., Sumaiyah, S., Utomo, A., Nuryawan, A., & Basyuni, M. (2021). Potential compounds from several Indonesian plants to prevent SARS-CoV-2 infection: A mini-review of SARS-CoV-2 therapeutic targets. Heliyon, 7, e06001 – e06001.
  17. A. Utomo, “Knowing When and How to Fight: COVID-19 Between Viral Clearance and Immune Tolerance,” Journal of Biomedicine and Translational Research, vol. 6, no. 2, pp. 63-73, Aug. 2020. https://doi.org/10.14710/jbtr.v6i2.8472
Books :
  1. Utomo, Ahmad R H. Memahami proses karsinogenesis kanker payudara. In: Farida Briani Sobri-Yohana Azhar-IGN Gunawan Wibisana Abdul Rachman, eds. Manajemen Terkini Kanker Payudara: Media Aesculapius; 2017: 29.
Conferences :
  1. (2013) Speaker KAVLI National Academy of Science (NAS) Session Personalized Medicine Overview of Current Practices, State of the Arts and Future Outlooks
  2. (2016) Oral Presentation. Respirology, 21: 20–79. Doi:10.1111/Resp.12939_14 Apsr6-0587: Frequent Baseline Egfr Mutation T790m In Cytological Specimens Of Tyrosine Kinase Inhibitor (Tki) Naive Adenocarcinoma Nsclc Patients
  3. (2017) Oral Presentation. Common And Uncommon Egfr Mutations Analysis In Cytology And Plasma Samples Of Treatment-Naive Lung Cancer Patients. Respirology, 22: 73. Doi:10.1111/Resp.13206_172
Awards :
  1. American Chemical Society Undergraduate Achievement Awards (1999)
  2. Carr Academic and Undergraduate Research Scholarship (1992-1999)
  3. American Lung Association (ALA) Senior Research Fellowship (2005-2007)
  4. YARSI Life Science Research Award (2017)